My research aims at understanding the origin and evolution of genomes. The genetic information of each living organism is encoded by a long sequence of four "characters". How this chain of characters encodes the structure of a full organism is the central question of molecular biology. Where it comes from, how it has evolved and still evolves is the scope of molecular evolution. By comparing genome sequences from various individual and/or species, one can gain insights into the process on how and when species are created, a fundamental aspect of life and therefore of biology.
In the lab, we're interested in understanding how biological molecule evolve. In order to do so, we combine modeling approaches and statistical data analysis, as well as lab experiments when possible. Our research make us wander in the fields of phylogenetics, population genomics and structural biology, as well as systems biology. One recurrent question we are addressing is how distinct levels of organization impact evolution.
More specific topic we are currently addressing include:
EDIT 14/01/17: position is now filled. Welcome Filipa! We currently have one open Ph-D ... Read MoreAnother case of "genome compartmentalization"
"Genome compartmentalization" has been described in several genomes of fungal ... Read MoreThe X chromosome involved in human-chimp speciation
This long-standing study is now published in PLoS Genetics. We demonstrate that the previously ... Read MoreMore Blog Entries